Endodermal sinus tumour of the vulva: an interesting clinico-pathological problem.

  • Peter S. Craighead, P F du Toit
  • Published 1993 in European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology


Endodermal sinus tumours (EST) of the lower female genital tract are uncommon malignancies. The majority of these involve the vagina and cervix, though there are a few case reports of tumours involving the vulva. These are usually either locally advanced or have metastatic disease present at initial diagnosis, and generally do badly on treatment. This case report discusses primary vulval involvement by EST. It shows that the absence of tumour markers can be misleading, and discusses the role of radiation and chemotherapy in the treatment of this rare disease.


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